GLP-3 RT is a novel tri-agonist peptide targeting GIP (glucose-dependent insulinotropic polypeptide), GLP-1 (glucagon-like peptide-1), and glucagon receptors. This synthetic peptide represents an advanced class of metabolic research compounds designed for investigating multi-receptor pharmacology and integrated metabolic pathway modulation.
Mechanism of Action
GLP-3 RT demonstrates balanced agonism across three incretin and glucagon receptor systems:
- GIP Receptor: Modulates insulin secretion and lipid metabolism
- GLP-1 Receptor: Regulates glucose homeostasis and satiety signaling
- Glucagon Receptor: Influences energy expenditure and hepatic glucose output
This tri-agonist architecture enables comprehensive investigation of synergistic metabolic pathway interactions in controlled experimental settings.
Research Applications
- Metabolic disease modeling and pathway analysis
- Incretin receptor pharmacology studies
- Multi-target therapeutic strategy development
- Comparative efficacy studies with mono- or dual-agonist peptides
- Receptor binding and signaling cascade investigations
- Pharmacokinetic and pharmacodynamic profiling
Quality Specifications
- Synthesized via solid-phase peptide synthesis (SPPS)
- Purity confirmed by HPLC and mass spectrometry
- Certificate of Analysis (CoA) included with each batch
- Endotoxin levels: <1.0 EU/mg
- Sterility tested per USP guidelines

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